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Cancer cells
Christiane has been producing these very cool images of mouse breast cancer cells. This are what we see in a fluorescence microscope at a magnification of about one thousand fold.
She used antibodies and fluorescent dyes to label specific cellular structures. The nuclei (that contains the DNA) is in blue, filamentous actin (which forms part of the cellular skeleton) is in red while the green indicates the presence of a surface protein called caveolin. Upon treatment with a specific hormone (bottom image), the cells become more agressive, more motile and the caveolin moves from the punctate structures at the surface to the inside of the cells.
March 16, 2005 |
Science
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